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Larry Alphs Selected Research

Paliperidone Palmitate

1/2023Feasibility study to evaluate capabilities for conducting psychiatric clinical research within the Rwandan mental healthcare system.
10/2022Evaluation of major treatment failure in patients with recent-onset schizophrenia or schizophreniform disorder: A post hoc analysis from the Disease Recovery Evaluation and Modification (DREaM) study.
1/2022The Disease Recovery Evaluation and Modification (DREaM) study: Effectiveness of paliperidone palmitate versus oral antipsychotics in patients with recent-onset schizophrenia or schizophreniform disorder.
10/2018An assessment of injection site reaction and injection site pain of 1-month and 3-month long-acting injectable formulations of paliperidone palmitate.
8/2018Projecting the Potential Effect of Using Paliperidone Palmitate Once-Monthly and Once-Every-3-Months Long-Acting Injections Among Medicaid Beneficiaries with Schizophrenia.
8/2018Paliperidone Palmitate 3-Monthly Versus 1-Monthly Injectable in Patients With Schizophrenia With or Without Prior Exposure to Oral Risperidone or Paliperidone: A Post Hoc, Subgroup Analysis.
1/2018Paliperidone palmitate once-monthly maintains improvement in functioning domains of the Personal and Social Performance scale compared with placebo in subjects with schizoaffective disorder.
1/2018Treatment effect with paliperidone palmitate compared with oral antipsychotics in patients with recent-onset versus more chronic schizophrenia and a history of criminal justice system involvement.
1/2018A quantitative systems pharmacology study on optimal scenarios for switching to paliperidone palmitate once-monthly.
1/2018Comparison of long-acting and oral antipsychotic treatment effects in patients with schizophrenia, comorbid substance abuse, and a history of recent incarceration: An exploratory analysis of the PRIDE study.
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Larry Alphs Research Topics

Disease

52Schizophrenia (Dementia Praecox)
01/2023 - 01/2003
18Psychotic Disorders (Schizoaffective Disorder)
10/2022 - 01/2003
7Weight Gain
11/2016 - 12/2009
6Headache (Headaches)
01/2018 - 11/2010
6Mania (Manias)
03/2016 - 11/2009
5Pain (Aches)
10/2018 - 05/2011
5Bipolar Disorder (Manic Depressive Psychosis)
10/2011 - 11/2009
4Sleep Initiation and Maintenance Disorders (Insomnia)
05/2015 - 11/2010
3Chronic Disease (Chronic Diseases)
01/2018 - 01/2012
3Sleepiness
11/2016 - 11/2010
2Major Depressive Disorder (Major Depressive Disorders)
10/2019 - 01/2019
2Mental Disorders (Mental Disorder)
01/2018 - 04/2017
1Movement Disorders (Movement Disorder)
01/2023
1Parkinson Disease (Parkinson's Disease)
01/2023
1Treatment-Resistant Depressive Disorder
01/2019
1Injection Site Reaction
10/2018
1Dizziness (Lightheadedness)
01/2018
1Nausea
01/2018
1Substance-Related Disorders (Drug Abuse)
01/2018
1Orthostatic Hypotension (Postural Hypotension)
11/2016
1Hyperprolactinemia
07/2015
1Hyperglycemia
07/2015
1Psychomotor Agitation (Akathisia)
05/2015
1Nasopharyngitis
03/2015
1Parkinsonian Disorders (Parkinsonism)
01/2013
1Tremor (Tremors)
01/2013
1Dyskinesias (Dyskinesia)
01/2013
1Delirium
02/2011

Drug/Important Bio-Agent (IBA)

43Paliperidone PalmitateFDA Link
01/2023 - 12/2009
35Antipsychotic Agents (Antipsychotics)IBA
01/2023 - 01/2004
15Risperidone (Risperdal Consta)FDA LinkGeneric
08/2018 - 12/2009
8asenapineFDA Link
11/2013 - 01/2007
7Olanzapine (Zyprexa)FDA Link
11/2013 - 01/2003
3Antidepressive Agents (Antidepressants)IBA
01/2019 - 10/2011
3Glucose (Dextrose)FDA LinkGeneric
11/2016 - 01/2012
2ProlactinIBA
11/2016 - 01/2012
2Clozapine (Clozaril)FDA LinkGeneric
01/2004 - 01/2003
1EsketamineIBA
01/2018
1HDL LipoproteinsIBA
11/2016
1Cholinergic Antagonists (Anticholinergics)IBA
11/2016
1CholesterolIBA
11/2016
1TabletsIBA
11/2016
1cyclo(Arg-Pro) (CI 4)IBA
07/2015
1LipidsIBA
02/2014
1Insulin (Novolin)FDA Link
02/2014
1Anti-Anxiety Agents (Anxiolytics)IBA
10/2011
1Aripiprazole (Abilify)FDA Link
11/2010
1Dihydrotachysterol (AT 10)IBA
04/2010
1Haloperidol (Haldol)FDA LinkGeneric
04/2010

Therapy/Procedure

30Injections
01/2023 - 12/2009
9Therapeutics
01/2019 - 01/2003
3Drug Therapy (Chemotherapy)
01/2019 - 10/2011
3Time-to-Treatment
01/2018 - 12/2014
3Secondary Prevention
03/2015 - 01/2012
2Patient Readmission
06/2014 - 10/2013
1Length of Stay
10/2019
1Aftercare (After-Treatment)
10/2011